Clinical study and nursing observation of effect of perioperative enteral immunonutrition on the host immune function in pancreatoduodenectomy patients
10.3760/cma.j.issn.1674-2907.2009.17.006
- VernacularTitle:胰十二指肠切除围手术期肠内免疫营养对机体免疫功能调节的影响与护理
- Author:
Lin WANG
1
;
Li-Hua FAN
;
Yi-Mei ZHANG
;
Ren LANG
Author Information
1. 黑龙江省齐齐哈尔市第一医院
- Keywords:
Panereatoduodenectomy;
Immune function;
Enteral Nutrition;
Immununutrition;
Nursing
- From:
Chinese Journal of Modern Nursing
2009;15(17):1620-1623
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of perioperative enteral immunonutrition on the host immune function in panereatoduodeneetomy patients,and nursing experience for enteral nutrition.Methods Forty pancreatoduodenectomy cases were divided into enteral immunonutrition(EIN)group and regular enteral nutrition (EN)group with 20 cases respectively.The complieations related to enteral nutrition were earefttlly observed.Host immunity function were measured by CD3,CD4,CD8,CD4/CDS,NK,IgG,IgM,IgA on pre-nutrition,pre-operative 1 day,postoperative 1,7,14,21 and 28 day.Results Forty cases all completed the study and smoothly recovered from operation.Compared with pre-nutrition,CD3,CD4 and NK were significantly increased and CD8 was significantly decreased in pre-operative 1 day.Synchronously,CD4/CD8 was significantly increased in EIN group,and its CD3 and CD4 was higher than EN group.Although cellular immune function was inhibited in postoperative 1 day,CD3 and NK of EIN group was higher than EN group.Cellular immune function began to recover from postoperative 14 day.Furthermore EIN and EN group obtained notable recovery on cellular immune function in postoperative 21 and 28 day respectively.Compared with pre-nutrition,all patients had higher level of lgA in pre-operative 1 day.At the time of postoperative 1,7,14,21 and 28 day,lgA was higher in EIN group than EN group.40 patients showed no complications such as flare and fistula inflammatory effusion and no enteral nutrition related complications in terms of obvious abdominal pain,diarrhea,abdominal distension.Conclusions Compared with regular enteral nutrition,enteral immunonutrition has advantages in relieving serious immune suppression,up-regulating cell immunity and humoral immunity.Fine nursing cares such as psychological nursing,perfect plan and finding the early complications of nutrition are the essentials for successful enteral nutri tion application.
