Clinical study on Alprostadil in the prevention of venous thrombosis among tumor patients after PICC indwelling

VernacularTitle:前列地尔预防肿瘤患者PICC置管后静脉血栓形成的临床研究
Author: Lin LIN ¹ ; Yan-Jie LIU ; Mu-Hong DENG
Author Information

1. 解放军总医院
Keywords: Alprostadil; PICC; Venous thrombosis; Tumor
From: Chinese Journal of Modern Nursing 2009;15(8):725-726
CountryChina
Language:Chinese
Abstract: Objective To study the effect of Alprostadil in the prevention of venous thrombosis among tumor patients after central venous catheter inserted through peripheral venous (PICC). Methods 137 patients with PICC were randomly divided into the control group and the experiment group. The control group received the routine nursing after indwelling catheter, while the experiment group received 10 ug of Alprostadi once a day for three days besides the routine nursing. Vascular ultrasonic examination was used to determine whether there was thrombosis among all of the patients after two months. The occurrence rates of thrombosis were compared between the two groups. Results The occurrence rate of thrombosis in the experiment group was lower than that in the control group (P<0.05). Conclusions Alprostadil can reduce the occurrence rate of venous thrombosis of tumor patients after PICC indwelling, so it can be an effective means for preventing thrombosis.