Effect of psychological intervention to anxiety-depression and T lymph cells in breast cancer patients during the peri-operation
10.3760/cma.j.issn.1674-2907.2008.22.004
- VernacularTitle:心理干预对围手术期乳腺癌患者焦虑抑郁及T淋巴细胞的影响
- Author:
Fong ZHAO
1
;
Yu-Ping BAI
;
Ming-Cui ZANG
;
Gui-Ying LIU
;
Jing-Yang LI
;
Cui-Yan LI
Author Information
1. 吉林大学第一医院
- Keywords:
Breast cancer;
Psychological intervention;
Anxiety;
Depression;
Tlymph cell
- From:
Chinese Journal of Modern Nursing
2008;14(22):2354-2357
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the affect of psychological intervention to anxiety-depression emotion and T Lvmlcih cells in breast cancer patients during the peri-operation. Methods We divided 60 cases into two groups at random. the experiment group(30) and the control group(30).The psychological situation Was evaluated according to the scores of Self-Rating Anxiety Status Inventory(SAS)and Depression Status Inventory (SDS).2 ml of venous blood Was taken to measure the level of T lymph cells. Then the experiment group Was given the specific and generalized psychological interventions. while the control group was given only the common nursing care. Results The scores of anxiety(8.65±3.69)and depression(31.70±5.79)after the intervention in the experiment group were lower than those before the intervention。and had significant difference (P<0.05).After the operation，the average value of CD3，CD4，CD4／CD8 in the experiment group was higber than that of the control group，and the values of CD3 and CD4 had statistical meaning(P<0.05).After the intervention，the vatues of CD3,CD4，CD4／CD8 of the experiment group were higher than those before the intervention. and the values of CD3 and CD4 had obvious difference(P<0.05).Conclusions In this study, a suitable and effective psychological intervention can improve the status of anxiety and depression of patients with breast cancer during the peri-operative period, and at the same time can modulate the immune status.
