A Case of Adrenal Cystic Pheochromocytoma with Contralateral Adrenocortical Adenoma Causing Subclinical Cushing's Syndrome.
10.3803/EnM.2012.27.4.323
- Author:
Chang Jun PARK
1
;
Joo Wan SEO
;
Hyeog Gyu SEOUNG
;
Jung Hee KOH
;
Yong Jae LEE
;
Bo Hyun KIM
;
In Ju KIM
Author Information
1. Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. pons71@hanmail.net
- Publication Type:Case Report
- Keywords:
Adrenocortical adenoma;
Cushing syndrome;
Pheochromocytoma
- MeSH:
Adrenal Gland Neoplasms;
Adrenalectomy;
Adrenocortical Adenoma;
Cushing Syndrome;
Dexamethasone;
Epinephrine;
Fatigue;
Female;
Headache;
Humans;
Hydrocortisone;
Korea;
Lymphoma;
Middle Aged;
Norepinephrine;
Pheochromocytoma;
Weight Gain
- From:Endocrinology and Metabolism
2012;27(4):323-328
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bilateral adrenal neoplasms are associated with metastatic cancer, pheochromocytoma and lymphoma. The coexistence of a unilateral functioning adrenocortical adenoma with contralateral pheochromocytoma is extremely rare. A 52-year-old woman complained of fatigue, headache, palpitation, and progressive weight gain. Hormonal assessment demonstrated high 24 hours urine epinephrine, norepinephrine, and free cortisol. A dexamethasone suppression test (overnight 1 mg, low dose 2 mg) showed insuppressible cortisol. Computerized tomographic scanning revealed a bilateral adrenal tumor. To preserve adrenal function, right adrenalectomy along with left adrenal tumorectomy was performed. Histological finding of the right adrenal tumor was pheochromocytoma and the left adrenal tumor was adrenocortical adenoma. This patient was the first case of a functional adrenocortical adenoma with contralateral cystic pheochromocytoma in Korea. We report the case with a review of the literature.
