Determination of the dominant language hemisphere by functional MRI in patients with temporal lobe epilepsy
10.3760/j.issn:0366-6999.2001.07.010
- VernacularTitle:颞叶癫痫语言皮层的功能性MRI定位研究
- Author:
Xiang GAO
1
;
Chengchuan JIANG
;
Chuanzhen LU
;
Tianzhen SHEN
Author Information
1. Huashan Hospital Shanghai Medical University
- Keywords:
functional MRI;
temporal lobe epilepsy;
language;
operation
- From:
Chinese Medical Journal
2001;114(7):711-713
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Objective To determine the dominant language hemisphere in patients with intractable temporal lobe epilepsy before surgical treatment by using functional MRI (fMRI). Methods Twelve patients underwent fMRI. Among them, 4 patients also underwent the Wada test. Anterior temporal lobectomy was performed on patients with epileptic focus on the non-dominant hemisphere, and selective amygdalo-hippocampectomy on patients with epileptic focus on the dominant hemisphere.Results Ten patients had left dominance, and 2 right dominance. The fMRI results were concordant with Wada test results in the 4 patients who accepted the Wada test. Seven patients underwent anterior temporal lobectomy, and 5 underwent selective amygdalo-hippocampectomy. There was no post-operative dysphasia. Conclusion fMRI is an alternative method of noninvasive functional mapping for language dominance in patients with temporal lobe epilepsy.
