Magnetic resonance imaging in distinguishing malignant from benign pleural disease
10.3760/j.issn:0366-6999.2001.06.019
- VernacularTitle:磁共振成像在良、恶性胸膜疾病鉴别诊断中的作用
- Author:
Liangping LUO
1
;
Bittner C ROLAND
;
Jincheng CHEN
;
Li HUANG
;
Hierholzer JOHANNES
Author Information
1. First Affiliated Hospital Jinan University Medical College
- Keywords:
pleural disease;
magnetic resonance imaging;
computed tomography
- From:
Chinese Medical Journal
2001;114(6):645-649
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of magnetic resonance imaging (MRI) in distinguishing malignant from benign pleural disease. Methods All 64 patients were examined with both computed tomography (CT) and MRI. The morphologic features of pleural lesions and MR signal intensity on T1-weighted, T2-weighted and contrast-enhanced T1-weighted images were evaluated. Results Mediastinal pleural involvement, circumferential pleural thickening, nodularity, irregularity of pleural contour, and infiltration of the chest wall and/or diaphragm were most suggestive of a malignant cause on CT and MR images. Contrary to what has been reported in the literature, pleural thickness greater than 1?cm either on CT or on MRI did not reveal a significant difference between malignant and benign pleural disease (P>0.05, chi-square test). Using morphologic features in combination with signal intensity features, MRI had a sensitivity of 98% and a specificity of 92% in the detection of pleural malignancy. Conclusions Compared with those on CT, the morphologic features on MRI allowed a mostly equal and in some cases superior detection and evaluation of the spread of pleural disease. In combination with signal intensity and morphologic features, MRI is very useful in distinguishing malignant from benign pleural disease.
