A Case of Primary Biliary Cirrhosis Mimicking Acute Hepatitis B in the Clinic, Republic of Korea.
10.4082/kjfm.2017.38.1.43
- Author:
Woo Hyuk KWON
1
;
Hong Min PARK
;
Jeong Jun PARK
;
Sung Hoon LEE
;
Yong Kyu LEE
Author Information
1. Department of Internal Medicine, Good Gang-An Hospital, Busan, Korea. lyk59@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Cholestasis;
Hepatitis;
Immunoglobulins;
Pruritus
- MeSH:
Antibodies;
Bile Ducts;
Biopsy;
Cholestasis;
Diagnosis;
Fatigue;
Hepatitis B Core Antigens;
Hepatitis B*;
Hepatitis*;
Humans;
Immunoglobulin M;
Immunoglobulins;
Liver;
Liver Cirrhosis, Biliary*;
Liver Diseases;
Outpatients;
Pruritus;
Republic of Korea*
- From:Korean Journal of Family Medicine
2017;38(1):43-46
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary biliary cirrhosis (PBC) is a slowly progressive cholestatic autoimmune liver disease characterized by progressive bile duct injury. The most common symptoms of this disease include fatigue and pruritus. The diagnosis of PBC is based on cholestatic biochemical liver tests, presence of antimitochondrial antibodies, and characteristic histological biopsy findings. We report a case of a patient with PBS, who was initially suspected to be in the window period of hepatitis B by a private doctor in a local clinic based on the detection of isolated immunoglobulin M antibody against hepatitis B core antigen. The presence of this antibody is the most useful index in diagnosing acute hepatitis B (+) by immunoserological test. The final diagnosis of the patient in Good Gang-An Hospital was PBC through additional tests. The patient is receiving outpatient treatment.
