Cost for several immuno-diagnostic systems in trichinosis developed in recent ten years
- Author:
Yan WEN
1
;
Yueqing ZHANG
;
Zhaoyong WU
;
Minjun HUANG
;
Zhibiao XU
Author Information
1. Beijing Tropical Medicine Research Institute
- From:
Chinese Medical Journal
1998;111(7):0-0
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the cost-effectiveness of various immuno-diagnostic systems for trichinosis and to find out the best testing system with low cost and high effectiveness.Methods The basic methods for the research are to difine and classify the direct and indirect cost for each testing system, and to identify a cost-effective testing system which would be practical and workable in case finding and/or mass survey. The data collected were analysed with parameters which are as follows: (1) the parameter of cost effectiveness expressed by cost/one sample in a given test that is unit cost. (2) the parameters of cost effectiveness: (a) for finding patients: cost/positive rate; (b) for examination carried out in normal individuals: cost/(100%-positive rate); (c) for the result of cross reaction: cost/(100%-cross reaction rate).Results Among the costs for detecting antibodies,the total costs vary from 98.06 yuan to 193.15 yuan. F-ELISA is the cheapest test. The unit cost for the five studied testing systems is ranging from 3.98 yuan to 4.22 yuan. According to the cost, the recommended order would be: F-ELISA, SPA-ELISA, ELISA, Western blot and IIP.Using the value of cost/effectiveness in analysis of the cost and comparing the results of detecting the positive cases ,the normal persons and cross reaction. The final results show that the methods for detecting antibodies are not only cheap but also practical and the preference for selection would be F-ELISA, ELISA and SPA-ELISA. The best method for detecting antigens is F-PcAb.Conclusions When these methods are used in practice, we suggest that F-ELISA should be the best method for choice in screening, when the result is positive, F-PcAb may be used for confirmation and can obtain a correct diagnosis.
