A Successful Bilateral Lung Transplantation in a Patient with High Panel Reactive Antibody and Positive Cross Matching.
- Author:
Jin San BOK
1
;
Jae Hyun JUN
;
Hyun Joo LEE
;
In Kyu PARK
;
Chang Hyun KANG
;
Jaeseok YANG
;
Young Tae KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Korea. ytkim@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Histocompatibility testing;
Lung transplantation;
Plasmapheresis
- MeSH:
Adult;
Biopsy;
Cryptogenic Organizing Pneumonia;
Extracorporeal Membrane Oxygenation;
Female;
Follow-Up Studies;
Histocompatibility Testing;
Humans;
Immunoglobulins;
Lung;
Lung Transplantation*;
Plasmapheresis;
Pneumonia;
Respiratory Insufficiency;
Stillbirth;
Ventilators, Mechanical;
Rituximab
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2014;47(4):420-422
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 44-year-old pregnant female patient gave stillbirth while being treated for pneumonia. She developed acute respiratory failure, which resulted in mechanical ventilator support. Diagnostic lung biopsy revealed a cryptogenic organizing pneumonia. The patient's condition deteriorated and a venous-venous extracorporeal membrane oxygenation was placed. She was listed for lung transplantation. Because of her worsening condition lung transplantation was performed despite positive cross matching result. She was treated with rituximab, intravenous immunoglobulin, and plasmapheresis and recovered without event. There is no sign of rejection at the time of last follow-up.
