Primary Sjogren's syndrome and its lymphoid malignancy: a report of four cases
- Author:
Yi DONG
1
;
Yan ZHAO
;
Xiaofeng ZENG
;
Donghong SUN
Author Information
1. Peking Union Medical College Hospital
- From:
Chinese Medical Journal
1998;111(3):218-219
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the incidence and spectrum of malignancy of primary Sjogren's syndrome (pSS).Methods 250 pSS who were followed-up in Peking Union Medical College (PUMC) Hospital were analyzed.Results Four of them were diagnosed with histopathological findings of 2 non-Hodgkin Lymphoma, 1 AILD, 1 multiple myeloma. Two died of secondary infection while receiving chemotherapy for lymphoma, 2 remained remitted.Conclusions The risk factors were persistent enlargement of major salivary glands, appearance of monoclonal serum Ig, and disappearance of auto antibodies.
