Anti-Sa antibody in Chinese rheumatoid arthritis
- Author:
Shangdong XU
1
;
Fulin TANG
;
Li SHI
;
Xiaodan GAN
;
Yangping SHI
;
Linjie CHENG
;
Jiarong LI
;
Yi DONG
Author Information
1. Peking Union Medical College Department of Rheumatology and Immunology PUMC Hospital
- From:
Chinese Medical Journal
1998;111(3):204-207
- CountryChina
- Language:Chinese
-
Abstract:
Objective To test anti-Sa antibody in different autoimmune connective tissue diseases and analyze the relationship between Sa antibody and clinical manifestations and laboratory tests in rheumatoid arthritis.Method Sa antigen was extracted from human placenta. Anti-Sa antibody was tested in 40 normal people and 478 connective tissue disease (CTD) patients using Western Blotting (WB). Conclusion Anti-Sa antibody was a new auto-antibody for the diagnosis of RA. Anti-Sa antibody positive patients seem to have more serious inflammation and more advanced disease process.
