Advances in electrowetting-on-dielectric digital microfluidics technology for disease diagnosis and prevention applications
10.3760/cma.j.cn112150-20231225-00492
- VernacularTitle:介电润湿数字微流控技术在疾病诊断及预防领域的研究进展
- Author:
Wenjie ZHU
1
;
Li WANG
;
Wei XIA
;
Xilong WANG
;
Jing JIN
;
Xin WANG
;
Yi LU
;
Ying CHEN
Author Information
1. 徐州医科大学医学技术学院，徐州 221004
- Keywords:
Digital microfluidic chip;
Electrowetting on dielectric;
Disease prevention;
Clinical application
- From:
Chinese Journal of Preventive Medicine
2024;58(7):1087-1095
- CountryChina
- Language:Chinese
-
Abstract:
Rapid and accurate diagnostic technologies are crucial for early detection and diagnosis of diseases. Electrowetting-on-dielectric digital microfluidics, with its high-precision detection and high-throughput screening capabilities, significantly enhances the accuracy and efficiency in early disease diagnosis and personalized treatment, enabling swift disease detection and widespread screening. This article provides a comprehensive review of the working principles and fabrication processes of digital microfluidic chips based on electrowetting on dielectric method. It details the latest research progress in the areas of nucleic acids, proteins, and cells, organizes the commercialization of digital microfluidics technology, and finally discusses the current challenges and future directions of digital microfluidic chips.
