Long-term prophylactic therapy combined with on-demand therapy for the control of hereditary angioedema——Comment on the 2021 edition of the international WAO/EAACI guideline for the management of hereditary angioedema
10.3760/cma.j.cn112150-20230712-00005
- VernacularTitle:长期预防性治疗结合按需治疗控制遗传性血管性水肿——2021版WAO/EAACI国际遗传性血管性水肿管理指南解读
- Author:
Huiying WANG
1
;
Yinshi GUO
;
Wo YAO
;
Lei CHENG
Author Information
1. 浙江大学医学院附属第二医院变态反应科,杭州 310009
- Keywords:
Hereditary angioedema;
On-demand treatment;
Long-term prophylactic therapy;
Guidelines
- From:
Chinese Journal of Preventive Medicine
2024;58(5):698-705
- CountryChina
- Language:Chinese
-
Abstract:
The 2021 edition of the international World Allergy Organization (WAO)/European Academy of Allergy and Clinical Immunology (EAACI) guideline for the management of hereditary angioedema (HAE) is mainly based on high-quality randomized controlled trials. It provides clinical classification for HAE and offers graded recommendations for on-demand therapy, short-term prophylactic therapy, and long-term prophylactic therapy. Additionally, it provides management strategies for people with different HAE types. This article focused on the interpretation of short-term, long-term prophylactic therapy and on-demand therapy for HAE, supplemented with the latest clinical evidence, aiming to provide references for the long-term management of HAE.