The role of preventive pancreatic duct stent placement in preventing acute pancreatitis after endoscopic retrograde cholangiopancreatography
10.3760/cma.j.cn112150-20211107-01032
- VernacularTitle:胰管支架置入在预防内镜逆行性胰胆管造影术后急性胰腺炎发生中的作用
- Author:
Qiaozhi ZHOU
1
;
Tianyu LIU
;
Yongqiu WEI
;
Ningning DONG
;
Junfeng GUO
;
Peng LI
;
Ming JI
;
Yinglin NIU
;
Yongjun WANG
;
Shutian ZHANG
Author Information
1. 首都医科大学附属北京友谊医院消化内科 国家消化系统疾病临床医学研究中心 首都医科大学消化病学系 消化疾病癌前病变北京市重点实验室，北京 100050
- Keywords:
Pancreatic duct stent;
Endoscopic retrograde cholangiopancreatography;
Pancreatitis
- From:
Chinese Journal of Preventive Medicine
2022;56(7):990-993
- CountryChina
- Language:Chinese
-
Abstract:
The aim of this study was to investigate the preventive effect of pancreatic duct stent on acute pancreatitis after endoscopic retrograde cholangiopancreatography. A retrospective analysis of the case data of patients who first underwent endoscopic retrograde cholangiopancreatography for choledocholithiasis in the Beijing Friendship Hospital from January 2015 to December 2019 for 5 years. According to whether the pancreatic duct stent was indwelled during the operation, they were divided into pancreatic duct stent group (147 cases) and non-indwelling pancreatic duct stent group (192 cases). The incidence of acute pancreatitis after endoscopic retrograde cholangiopancreatography was compared between the two groups according to COTTON criteria. Independent sample t test, Pearson Chi-square test (χ 2) and Fisher′s exact test were used to compare groups′ differences. There were 2 cases of acute pancreatitis in the pancreatic duct stent group, all of which improved after 48 hours. There were 22 cases of acute pancreatitis in the non-indwelling pancreatic duct stent group, of which 20 cases improved within 48 hours, and the other 2 cases had severe pancreatitis, which improved and discharged after 30 days of treatment. There was significant difference in the incidence of acute pancreatitis between the pancreatic duct stenting group (1.4%) and the group without placement of pancreatic duct stents (11.5%) (χ2=12.905, P<0.001). In conclusion, Pancreatic duct stent may be an effective method to prevent PEP.
