Research advances in the adverse effects of azo dyes

VernacularTitle:偶氮染料毒性效应研究进展
Author: Fuchang DENG ¹ ; Chao WANG ; Wen GU ; Yuanyuan CHEN ; Jiajun HAN ; Huamao DU ; Hui PENG ; Song TANG
Author Information

1. 中国疾病预防控制中心环境与人群健康重点实验室　中国疾病预防控制中心环境与健康相关产品安全所，北京　100021
Keywords: Toxic actions; Carcinogens, environmental; Endocrine disruption; Disperse dyes
From: Chinese Journal of Preventive Medicine 2020;54(12):1478-1483
CountryChina
Language:Chinese
Abstract: China is the world′s largest producer and user of dyes. The mass production and widespread use of disperse azo dyes led to environmental pollutions and potential human health risks. Azo dyes in environmental media (i.e., water, soil, air, and dust), food and clothing can enter the human body through multiple exposure routes, and some of them can be metabolized to produce more toxic metabolites, which can trigger toxic effects such as allergic reactions, tumor formation, and endocrine disruptions. This study systematically reviewed the production and use of azo dyes, environmental concentrations, human exposures, toxic effects and their underlying mechanisms, and regulations and standards. Meanwhile, the research trends of azo dyes were also discussed.