Cytomegalovirus detoxification and associated factors among preschool children in Yi′nan County
10.3760/cma.j.cn112150-20200420-00603
- VernacularTitle:沂南县学龄前儿童中巨细胞病毒排毒状况及相关因素分析
- Author:
Xiaolin LIU
1
;
Xingqu XU
;
Qishu FENG
;
Chengzong LIU
;
Guirong LI
;
Jidong LU
;
Xuemei YUAN
;
Aiqiang XU
Author Information
1. 山东省疾病预防控制中心病原微生物所 山东省传染病预防控制重点实验室 山东大学预防医学研究院，济南250014
- Keywords:
Cytomegalovirus;
Child;
Epidemiology;
Detoxification;
Associated factors
- From:
Chinese Journal of Preventive Medicine
2020;54(10):1111-1114
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate cytomegalovirus detoxification and associated factors among preschool children in Yinan County, Shandong Province.Methods:Two kindergartens were selected from the county and township of Yinan respectively. A total of 250 children were investigated in October 2018. Case information was obtained through the child′s guardian. Saliva samples of children and their mothers were collected for cytomegalovirus realtime-PCR detection.The status of CMV detoxification of children was explored and the associated factors were analyzed.Results:A total of 242 preschool children were investigated, and the detoxification rate of cytomegalovirus among them was 22.31% (54/242, 95% CI: 17.0%-27.6%). Logistic regression analysis showed that the rate of detoxification was higher in children whose mothers were cytomegalovirus detoxified ( OR=12.39, 95% CI:1.73-88.65)and whose school was located in the county ( OR=3.58 ,95% CI:1.34-9.55). Conclusions:The detoxification rate of cytomegalovirus in preschool children is high, and there is mutual transmission between children and mothers. Women of childbearing age should pay attention to prevent congenital cytomegalovirus infection when they come into contact with children.
