Research progress on toxic effects and biomarkers of organophosphate ester flame retardant exposures
10.3760/cma.j.cn112150-20200611-00868
- VernacularTitle:有机磷酸酯阻燃剂暴露的毒性效应及生物标志物研究进展
- Author:
Yuanzheng FU
1
;
Yali SHI
;
Xiaobo LU
;
Song TANG
Author Information
1. 中国疾病预防控制中心环境与人群健康重点实验室 中国疾病预防控制中心环境与健康相关产品安全所,北京 100021
- Keywords:
Phosphoric acid esters;
Environmental exposure;
Toxic actions;
Biomarker
- From:
Chinese Journal of Preventive Medicine
2020;54(10):1152-1160
- CountryChina
- Language:Chinese
-
Abstract:
Organophosphate ester (OPEs) has been widely used as a substitute of brominated biphenyl ethers and other brominated flame retardant (BFRs), and their health effects and environmental impacts are widely concerned. This article systematically reviews the common types, metabolites, environmental occurrences, exposure pathways, levels, toxic effects and biomarkers of OPEs, in order to explore the relationships between OPEs exposures and biomarkers, to reveal the potential mechanisms of health effects, and to provide references and scientific basis for the health effects of OPEs exposure in China.