Patient-reported outcomes of locally advanced gastric cancer undergoing robotic versus laparoscopic gastrectomy: a randomized controlled study
10.3760/cma.j.cn112139-20230414-00164
- VernacularTitle:机器人与腹腔镜胃切除术治疗局部进展期胃癌的患者报告结局的单中心随机对照研究
- Author:
Qingrui WANG
1
;
Shougen CAO
;
Cheng MENG
;
Xiaodong LIU
;
Zequn LI
;
Yulong TIAN
;
Jianfei XU
;
Yuqi SUN
;
Gan LIU
;
Xingqi ZHANG
;
Zhuoyu JIA
;
Hao ZHONG
;
Hao YANG
;
Zhaojian NIU
;
Yanbing ZHOU
Author Information
1. 青岛大学附属医院胃肠外科，青岛 266003
- Keywords:
Stomach neoplasms;
Gastrectomy;
Robotics;
Laparoscopy;
Patient-reported outcomes;
Clinical outcomes
- From:
Chinese Journal of Surgery
2024;62(1):57-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the patient-reported outcomes and short-term clinical outcomes between robotic-assisted and laparoscopic-assisted radical gastrectomy for locally advanced gastric cancer.Methods:This single-center prospective randomized controlled trial was conducted in the Department of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University from October 2020 to August 2022. Patients with locally advanced gastric cancer who were to undergo radical gastrectomy were selected and randomly divided into two groups according to 1∶1, and received robotic surgery and laparoscopic surgery, respectively. Patient-reported outcomes and short-term clinical outcomes (including postoperative complications, surgical quality and postoperative short-term recovery) were compared between the two groups by independent sample t test, Mann-Whitney U test, repeated ANOVA, generalized estimating equation, χ2 test and Fisher′s exact test. Results:A total of 237 patients were enrolled for modified intention-to-treat analysis (120 patients in the robotic group, 117 patients in the laparoscopic group). There were 180 males and 59 females, aged (63.0±10.2) years (range: 30 to 85 years). The incidence of postoperative complications was similar between the robotic group and laparoscopic group (16.7% (20/120) vs. 15.4% (18/117), χ2=0.072, P=0.788). The robotic group had higher patient-reported outcomes scores in general health status, emotional, and social domains compared to the laparoscopic group, differences in time effect, intervention effect, and interaction effect were statistically significant (general health status: χ2 value were 275.68, 3.91, 6.38, P value were <0.01, 0.048, 0.041; emotional: χ2 value were 77.79, 6.04, 6.15, P value were <0.01, 0.014, 0.046; social: χ2 value were 148.00, 7.57, 5.98, P value were <0.01, 0.006, 0.048). However, the financial burden of the robotic group was higher, the differences in time effect, intervention effect and interaction effect were statistically significant ( χ2 value were 156.24, 4.08, 36.56, P value were <0.01, 0.043,<0.01). Conclusion:Compared to the laparoscopic group, the robotic group could more effectively relieve postoperative negative emotions and improve recovery of social function in patients.
