The clinical practice and consideration for donor liver expansion
10.3760/cma.j.cn112139-20230607-00228
- VernacularTitle:拓展供肝来源的临床实践与若干思考
- Author:
Kai WANG
1
;
Fengqiang GAO
;
Xiao XU
Author Information
1. 浙江大学医学院 浙江大学器官移植研究所 浙江省肿瘤融合研究与智能医学重点实验室，杭州 310058
- Keywords:
Liver transplantation;
Donor selection;
Organ shortage;
Liver donor pool;
Marginal donor liver;
Xenograft;
Stem cell
- From:
Chinese Journal of Surgery
2023;61(10):826-832
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation is the most effective method to address end-stage liver disease. However, there is a huge imbalance between organ supply and demand in China. Recently,effective expansion of the donor liver has become a hot research direction in academia. Authors′ group comprehensively integrates domestic and foreign evidence-based medical evidence, the latest academic outcomes and clinical experience. Based on the innovative viewshed of crossfusion between biomedical engineering and medicine, author group systematically elaborate in the main strategies for expanding the liver donor pool, including the multichannel expansion of marginal donor liver,multidimensional innovation of technologies in transplant surgery and diversified exploration of alternative resources of organs. The author group aims to promote the construction of a large cohort,the integration of big data,and the output of high quality research,achieving innovative theory and clinical translation in organ transplantation,thus promoting the higher quality development of liver transplantation in China.
