Advance in immunotherapy on biliary tract cancers
10.3760/cma.j.cn112139-20200515-00382
- VernacularTitle:免疫治疗在胆道恶性肿瘤中的应用进展
- Author:
Liguo LIU
1
;
Yijian ZHANG
;
Xu′an WANG
;
Yingbin LIU
Author Information
1. 上海交通大学医学院附属仁济医院胆胰外科 上海市胆道疾病研究重点实验室 上海市胆道疾病研究中心 癌基因及相关基因国家重点实验室 200127
- Keywords:
Biliary neoplasms;
Immunotherapy;
Checkpoint receptor inhibitors;
Adoptive cell therapy;
Tumor vaccine
- From:
Chinese Journal of Surgery
2021;59(2):156-160
- CountryChina
- Language:Chinese
-
Abstract:
Biliary tract cancers(BTC),including gallbladder cancer and cholangiocarcinoma,has the characteristics of low early diagnosis rate,complex anatomy,insensitivity to radiotherapy and chemotherapy, and poor prognosis.In recent years,immunotherapy as a new method,has made great progress in the treatment of advanced malignant tumors.Immunotherapy is gradually applied in the treatment of BTC,such as inhibitory agents targeting the immune checkpoint receptor pathway,adoptive immunotherapy and tumor vaccines.