Comparison of Early and Mid-Second-Trimester Amniocentesis.
- Author:
Hyun Kyong ANN
;
Hyun Mee RYU
;
Moon Young KIM
;
En Sung KIM
;
Ha Kyun SONG
;
Hwan Kyoun LEE
;
Jung Ryeol HAN
;
Jin Mee KIM
;
Soo Kyung CHOI
;
Ho Won HAN
- Publication Type:Original Article
- Keywords:
Early amniocentesis;
Genetic evaluation
- MeSH:
Amniocentesis*;
Amniotic Fluid;
Female;
Pregnancy;
Premature Birth;
Prenatal Diagnosis
- From:Korean Journal of Obstetrics and Gynecology
1997;40(1):123-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We sought to determine whether early amniocentesis is a safe and acceptable method of genetic evaluation in early pregnancy. During the 20-month period from February 1994 to September 1995, 80 consecutive early amniocentesis were performed transabdominally at 12(+3)-14(+6) weeks of gestation and 305 consecutive mid-second-trimester transabdominal amniocenteses were performed at 16(+0)-18(+0) weeks of gestation. All amniotic fluid samples were cultured using flask method. There were no significant differences between the early and mid-second-trimester amniocenteses in failed sampling, ambiguous results, pregnancy loss within 4 weeks after the procedure, pregnancy loss from 4 weeks after procedure to 28 weeks of gestation, preterm birth, and perinatal death. We may conclude that early amniocentesis is a safe and acceptable method for prenatal diagnosis.
