Mid-to long-term outcomes of cervical disc arthroplasty for symptomatic cervical disc disease：a meta-analysis
10.3760/cma.j.issn.0529-5815.2016.12.012
- VernacularTitle:颈椎间盘置换术治疗颈椎病中长期疗效及安全性的Meta分析结果
- Author:
Shunli KAN
1
;
Bo YANG
;
Guangzhi NING
;
Shijie GAO
;
Jingcheng SUN
;
Shiqing FENG
Author Information
1. 300052,天津医科大学总医院骨科
- Keywords:
Spinal fusion;
Cervical vertebrae;
Treatment outcome;
Meta-analysis
- From:
Chinese Journal of Surgery
2016;54(12):935-939
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the benefits and harms of cervical disc arthroplasty ( CDA) with anterior cervical discectomy and fusion( ACDF) for symptomatic cervical disc disease at mid? to long?term follow?up? Methods Electronic searches were made in PubMed,EMBASE,and the Cochrane Library for randomized controlled trials with at least 48 moths follow?up?Outcomes were reported as relative risk or standardized mean difference?Meta?analysis was carried out using Revman version 5?3 and Stata version 12?0. Results Seven trials were included, involving 2 302 participants?The results of this meta?analysis indicated that CDA brought about fewer secondary surgical procedures,lower neck disability index (NDI) scores,lower neck and arm pain scores,greater SF?36 Physical Component Summary (PCS) and Mental Component Summary( MCS) scores,greater range of motion ( ROM) at the operative level and less superior adjacent?segment degeneration ( P<0?05 ) than ACDF?CDA was not statistically different from ACDF in inferior adjacent?segment degeneration,neurological success,and adverse events (P>0?05)? Conclusions CDA can significantly reduce the rates of secondary surgical procedures compared with ACDF?Meanwhile, CDA is superior or equivalent to ACDF in other aspects?As some studies without double?blind are included and some potential biases exites,more randomized controlled trials with high quality are required to get more reliable conclusions.
