Ultrasonographic Features of Papillary Thyroid Carcinoma in Patients with Graves' Disease.
10.3904/kjim.2010.25.1.71
- Author:
Jin Ook CHUNG
1
;
Dong Hyeok CHO
;
Dong Jin CHUNG
;
Min Young CHUNG
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. mychung@chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
Graves disease;
Thyroid neoplasms;
Ultrasonography
- MeSH:
Adult;
Carcinoma, Papillary/*ultrasonography;
Female;
Graves Disease/*ultrasonography;
Humans;
Male;
Middle Aged;
Retrospective Studies;
Thyroid Gland/*ultrasonography;
Thyroid Neoplasms/*ultrasonography;
Ultrasonography/*methods
- From:The Korean Journal of Internal Medicine
2010;25(1):71-76
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: To characterize ultrasonographic findings in papillary thyroid carcinoma (PTC) combined with Graves' disease. METHODS: Medical records and ultrasonographic findings of 1,013 patients with Graves' disease and 3,380 patients without Graves' disease were analyzed retrospectively. A diagnosis of PTC was based on a pathologic examination. RESULTS: The frequency of hypoechogenicity was lower in patients with PTC and Graves' disease than in patients with PTC alone (p < 0.05). The frequency of perinodular blood flow in patients with PTC and Graves' disease was significantly higher than in those with PTC alone (p < 0.05). PTC combined with Graves' disease was characterized by more ill-defined borders and less frequency of overall calcification, punctate calcification, and heterogeneous echogenicity, although the difference was not statistically significant. CONCLUSIONS: Our results suggest that patients with Graves' disease more frequently have atypical PTC findings on ultrasonography.
