A Case of Liver Metastasis of Gastrointestinal Stromal Tumor That Was Resected after Treatment with Imatinib Mesylate and Sunitinib.
- Author:
Gum O JUNG
1
;
Kwon Mook CHAE
;
Dong Eun PARK
;
Hyeok SHIM
;
Sang Hyun PARK
;
Ki Jung YUN
Author Information
1. Department of Surgery, Wonkwang University Hospital, Wonkwang University College of Medicine, Korea. chaekm@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Gastrointestinal stromal tumors;
Imatinib mesylate;
Liver metastasis;
Liver resection
- MeSH:
Benzamides;
Biopsy;
Follow-Up Studies;
Gastric Fundus;
Gastrointestinal Stromal Tumors;
Hepatectomy;
Humans;
Indoles;
Liver;
Mesylates;
Neoplasm Metastasis;
Piperazines;
Pyrimidines;
Pyrroles;
Imatinib Mesylate
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2010;14(4):262-266
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 65-year old man underwent wedge resection for a gastrointestinal stromal tumor (GIST) of the gastric fundus in 1997. In 2003, the abdominal CT and sono-guided biopsy revealed he had a large GIST liver metastasis. He underwent treatment with 400 mg/day of imatinib mesylate. As a result, the liver metastasis markedly decreased in size. However, focal progression of the liver metastasis was observed on the follow up CT, so we increased the imatinib from 400 mg/day to 800 mg/day. We then performed extended left hepatectomy. We report here on a patient who presented with an isolated metastatic GIST to the liver, and the patient was successfully treated with imatinib therapy and hemihepatectomy.
