An Experience of Cord Blood Transfusion in Cold Hemagglutinin Disease Associated with Mycoplasma pneumoniae Infection.
- Author:
Woon Hyoung LEE
1
;
Chang Kee KIM
;
Hyun Ok KIM
;
Hae Sik KWON
;
Chuhl Joo LYU
Author Information
1. Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. hyunok1019@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Cold hemagglutinin disease;
Cord blood transfusion;
Cold-reactive autoantibody
- MeSH:
Anemia, Hemolytic;
Erythrocytes;
Fetal Blood*;
Hemagglutinins*;
Humans;
Male;
Mycoplasma pneumoniae*;
Pneumonia, Mycoplasma*;
Sensitivity and Specificity
- From:The Korean Journal of Laboratory Medicine
2003;23(4):279-281
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of cold hemagglutinin disease associated with Mycoplasma pneumoniae infection treated with cord blood transfusion. Cold hemagglutinin disease is a hemolytic anemia most commonly associated with cold-reactive autoantibody with anti-I specificity. On the basis of the fact that the level of I antigen on cord red blood cells is extremely low, a six year old male patient was transfused with 60 mL of ABO blood type-matched, cord blood. No complication from the transfusion was observed. Due to the deficiency in cord blood supply, filtered irradiated RBC 100 mL was transfused three times thereafter. The hemoglobin level began to increase from the fifth hospital day. The patient was discharged without additional transfusion on the eleventh hospital day. No remarkable complications were noted at the time of discharge.
