Influence of non-diabetic hyperglycemia on postoperative complications following laparoscopic colorectal cancer resection
10.3760/cma.j.issn.1671-0274.2015.07.013
- VernacularTitle:非糖尿病性高血糖对腹腔镜结直肠癌根治术后并发症的影响
- Author:
Chunping ZENG
1
;
Youping CHEN
;
Qingshui YANG
;
Xinfang LIAO
Author Information
1. 南方医科大学附属南海医院内分泌科
- Keywords:
Non-diabetic hyperglycemia;
Colorectal neoplasms;
Postoperative complications
- From:
Chinese Journal of Gastrointestinal Surgery
2015;(7):684-687
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of non-diabetic hyperglycemia on postoperative complications following laparoscopic colorectal cancer resection. Methods Clinical data of 636 patients undergoing laparoscopic colorectal cancer resection in The Affiliated Nanhai Hospital of Southern Medical University between 2009 and 2013 were analyzed retrospectively. After excluding cases with diabetes mellitus, the patients were divided into the hyperglycemia group(blood glucose level> 7.8 mmol/L at any time during hospitalization period, n=161) and the non-hyperglycemia grou p (n=309). Results Compared to non-hyperglycemia group, hyperglycemia group had more intraoperative blood loss [(186±80) ml vs. (158±74) ml, P=0.007] and longer postoperative hospital stay [(14.0± 6.8) d vs. (11.2 ±5.5) d, P=0.013]. The overall rate of postoperative complication was 24.8% and 16.5% respectively (P=0.030), in the hyperglycemia and the non-hyperglycemia groups, and the mortality was 1.2% and 0.6% respectively(P=0.541). Multivariable analysis showed hyperglycemia was an independent risk factor of postoperative complication (RR=2.425, 95% CI:1.210-4.226, P=0.006). Conclusions Non-diabetic hyperglycemia may increase the risk of postoperative complications following laparoscopic colorectal cancer resection. Perioperative blood glucose monitoring should be performed, regardless of patients with or without diabetes.
