Clinical Findings and Therapy of Ureteral Duplication in 61 Children.
- Author:
Pyung Kil KIM
;
Sang Won HAN
;
Ji Hong KIM
;
Jin Won YOOK
- Publication Type:Original Article
- Keywords:
Curschmann's spiral;
Cervico-vaginal smear
- MeSH:
Child;
Male;
Female;
Humans;
Biopsy
- From:Journal of the Korean Society of Pediatric Nephrology
1998;2(2):169-177
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Osteoclast-like giant cell tumor of the liver is an extremely rare malignancy with poor prognosis. To our knowledge, 5 cases have been reported in English literatures, but there was no report about fine needle aspiration cytologic(FNAC) features. We experienced a case of osteoclast-like giant cell tumor of the liver obtained by computed tomography(CT)-guided FNAC and needle biopsy. The cytologic findings mimicked giant cell tumor of the bone. A large hepatic mass of the left lobe with abdominal wall invasion was found by CT in a 46- year-old female complaining of epigastric pain. The FNAC showed moderately cellular smears consisting of osteoclast-like giant cells and mononuclear cells, which were individually scattered or intermingled in clusters. The osteoclast-like giant cells had abundant cytoplasms and multiple small round nuclei with fine chromatin and distinct nucleoli. The mononuclear cells had moderate amount of cytoplasm and relatively bland-looking oval nuclei with single small nucleoli. All of the cytologic features recapitulated the histologic findings of bland-looking osteoclast-like multinucleated giant cells evenly dispersed throughout the background of mononuclear cell. The immunohistochemical study showed positive reaction for CD68 and vimentin, but negative for cytokeratin in both osteoclast-like giant cells and mononuclear cells.
