Risk factors of reoperation for remnant stomach cancer
10.3760/cma.j.issn.1671-0274.2015.02.011
- VernacularTitle:残胃再发癌二次手术根治性的影响因素分析
- Author:
Zhenchi MA
1
;
Rupeng ZHANG
;
Weijia WANG
;
Xuejun WANG
;
Qiang XUE
;
Han LIANG
Author Information
1. 300060,天津医科大学肿瘤医院胃部肿瘤科 国家肿瘤临床医学研究中心 天津市肿瘤防治重点实验室
- Keywords:
Remnant stomach cancer;
Reoperation;
Radical operation;
Risk factors
- From:
Chinese Journal of Gastrointestinal Surgery
2015;(2):139-142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the risk factors influencing patients with recurrent remnant stomach cancer to receive radical re-resection. Methods Clinicopathological data of 93 patients undergoing reoperation because of postoperative local recurrence of gastric carcinoma in Tianjin Medical University Cancer Institute and Hospital from January 2003 to May 2014 were analyzed retrospectively. Patients were divided into radical re-resection group and non-radical re-operation group. The characteristics of two groups were compared and evaluated by univariate and multivariate analysis. Results Among 93 patients, 41 were treated by radical re-resection and 52 by non-radical re-operation. Univariate analysis showed that reconstruction , lymph nodes dissection extent, N stage, TNM stages of the initial operation, interval between initial operation and recurrence, presenting symptoms, the interval between clinical symptom appearance or definite diagnosis and re-resection, tumor markers increasing before re-operation were significant factors associated with the chance to receive radical reoperation (P<0.05). Multivariate Logistic regression analysis revealed presenting symptoms (RR=3.684, 95% CI:1.233-11.009, P=0.020) and TNM stages of initial operation (RR=0.266, 95% CI:0083-0.853, P=0.026) were independent factors associated with the chance to radical reoperation (P<0.05). Conclusions Symptomatic recurrence and advanced TNM stages of initial operation are independent risk factors associated with patients who develope local recurrence of remnant stomach cancer to receive radical reoperation.
