Current study and application of human colorectal cancer cell lines
10.3760/cma.j.issn.1671-0274.2015.01.027
- VernacularTitle:人结直肠癌细胞株研究及使用现状
- Author:
Keling CHEN
1
;
Zhaoying LYU
;
Zongguang ZHOU
;
Yuan LI
Author Information
1. 四川大学生物治疗国家重点实验室消化外科研究室
- Keywords:
Colorectal neoplasms;
Cell lines;
Classification;
Choice;
Application present situation
- From:
Chinese Journal of Gastrointestinal Surgery
2015;(1):93-97
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer(CRC) cell lines are ideal in vitro models for colorectal cancer study. Although the number of colorectal cell lines increases hence provides diversified choices for research, several problems occur including the uneven quality control, insufficient attention to the origin and biological characteristics of CRC cell lines , resulting in inappropriate selection of CRC cell lines for study. In this paper, we classify the current CRC cell lines for study, review the biological characteristics, current problems of experiment choices, and discuss the exact choice of cell lines for CRC study.
