Comparison of oncologic clearance and long-term outcomes of laparoscopic surgery versus open ;surgery in radical resection of rectal cancer
10.3760/cma.j.issn.1671-0274.2014.08.009
- VernacularTitle:腹腔镜与开腹直肠癌根治术肿瘤切除完整性及长期疗效的比较
- Author:
Xiaowen XU
1
;
Xu LI
;
Chuangang FU
;
Wei ZHANG
;
Enda YU
;
Hantao WANG
;
Liqiang HAO
;
Qun QIU
Author Information
1. 第二军医大学长海医院结直肠外科
- Keywords:
Rectal neoplasms;
Laparoscopy;
Radical surgery;
Long-term outcomes
- From:
Chinese Journal of Gastrointestinal Surgery
2014;(8):772-775
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the oncologic clearance and long-term outcomes between laparoscopic surgery and open surgery in radical resection of rectal cancer. Methods Clinicopathological and follow-up data of 1184 cases with rectal cancer undergoing radical resection from July 2005 to December 2011 were analyzed retrospectively. According to the surgical method , cases were divided into laparoscopy group (104 cases) and open group (1080 cases). Demographics, number of harvested lymph nodes, distance between distal margin and tumor, incidence of anastomotic complications, disease-free survival (DFS) and overall survival (OS) were compared between the two groups. Results There were no significant differences in the number of harvested lymph nodes(15.5 vs. 14.4, P>0.05), length of distal margin (2.5 cm vs. 2.1 cm, P>0.05) and incidence of anastomotic complications (1.9% vs. 1.9%, P>0.05) between the two groups. And there were no significant differences in DFS and OS between the two groups (both P>0.05). The 3-year and 5-year DFS in laparoscopy group were 79.0% and 69.3%, and were 78.0% and 72.5% in open group. The 3-year and 5-year OS in laparoscopy group were 93.5% and 81.2%, which were 87.6% and 80.7% in open group. There were no significant differences in DFS and OS after stratification by TNM stage. Conclusion The oncologic clearence and long-term outcomes after laparoscopic surgery are comparable with open surgery in radical resection of rectal cancer.
