A Case of Extrapontine Myelinolysis with both Frontal Lobe Dysfunction and Decreased Perfusion in SPECT.
- Author:
Seung Hoi LEE
1
;
Bong Kee CHOI
;
Hak Seung LEE
;
Han Saem LEE
;
Seong Wook PARK
;
Hyuk CHANG
;
Yo Sik KIM
;
Kwang Ho CHO
;
Hak Ryul KIM
;
Eun Tak JUNG
Author Information
1. Department of Neurology, Wonkwang University School of Medicine, 344-2 Sinyong-dong, Iksan-si, Jeonbuk-do, 570-180, Korea. yosik@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
EPM;
Hyperosmolarity;
Frontal lobe dysfunction
- MeSH:
Brain;
Bronchi;
Dihydroergotamine;
Drug Therapy;
Female;
Frontal Lobe*;
Humans;
Hyperglycemia;
Hypernatremia;
Magnetic Resonance Imaging;
Memory;
Myelinolysis, Central Pontine*;
Osmolar Concentration;
Perfusion*;
Steroids;
Tomography, Emission-Computed, Single-Photon*
- From:Journal of the Korean Neurological Association
2003;21(2):195-198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A thirty-nine year old woman was consulted because of personality change, agitation and memory disturbance. She received chemotherapy and oral steroids because of carcinoma within the bronchus. She had a high serum osmolarity caused by hyperglycemia and hypernatremia, and it was corrected rapidly. Her brain MRI showed EPM (extrapontine myelinolysis). Brain SPECT showed hypoperfusion in the bilateral orbitofrontal regions. We report a patient with EPM with typical frontal lobe dysfunction as an initial manifestation and bilateral orbitofrontal hypoperfusion.
