Focused Update of Korean Clinical Practice Guidelines for the Thrombolysis in Acute Stroke Management.
- Author:
Kyung Hee CHO
1
;
Sang Bae KO
;
Dae Hyun KIM
;
Hee Kwon PARK
;
A Hyun CHO
;
Keun Sik HONG
;
Kyung Ho YU
;
Ji Hoe HEO
;
Sun Uck KWON
;
Hee Joon BAE
;
Chang Wan OH
;
O Ki KWON
;
Byung Chul LEE
;
Byung Woo YOON
;
Joung Ho RHA
Author Information
1. Department of Neurology, Korea University College of Medicine, Seoul, Korea.
- Publication Type:Practice Guideline ; Original Article
- Keywords:
Clinical practice guideline;
Ischemic stroke;
Acute treatment;
Thrombolysis;
Intravenous;
Intra-arterial;
Mechanical;
Recanalization
- MeSH:
Aged;
Humans;
Stroke;
Thrombolytic Therapy;
Tissue Plasminogen Activator
- From:Korean Journal of Stroke
2012;14(3):95-105
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Since the release of first Korean Clinical Practice Guideline of Stroke in 2009, many important new evidences have emerged in the field of thrombolytic therapy. Among the recent developments are the extended therapeutic time window of intravenous (IV) tissue plasminogen activator (tPA) up to 4.5 hours after onset, and the efforts for the wider application of IV thrombolysis to patients with minor stroke and elderly patients over 80 years old. Debates about the optimal dose of IV tPA according to the ethnic population is still ongoing. Further evidences for the efficacy of intra-arterial thrombolysis have also accumulated, including the application of various novel mechanical devices with promising results. Thus update of guideline became necessary and we revise the acute stroke management guideline, focusing on the thrombolytic therapy.
