Clinical analysis of transnasal endoscopic low temperature plasma radiofrequency ablation in treatment of children with snoring
- VernacularTitle:经鼻内镜下低温等离子射频消融术治疗小儿鼾症的临床分析
- Author:
Wenxia JI
1
;
Ran WANG
;
Qing HUANG
;
Jie LI
Author Information
- Keywords: snoring in children; transnasal endoscopic low temperature plasma radiofrequen-cy ablation; ventilation function; quality of sleep
- From: Journal of Clinical Medicine in Practice 2023;27(24):77-81
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the efficacy and postoperative complications of transnasal en-doscopic low temperature plasma radiofrequency ablation in the treatment of children with snoring.Methods Clinical materials of 278 children with snoring were analyzed retrospectively,and they were divided into control group(n=128)and observation group(n=150)according to different op-eration methods.The control group was treated with adenoidectomy and bilateral tonsillectomy,while the observation group was treated with transnasal endoscopic low temperature plasma radiofrequency ablation.Perioperative indicators,the Visual Analogue Scale(VAS)score,inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin-4(IL-4)and interleukin-8(IL-8)],stress response indicators[malondialdehyde(MDA),superoxide dismutase(SOD)and glutathione(GSH)],venti-lation function indicators[apnea hyponea index(AHI),oxygen desaturation index(ODI),the lon-gest apnea time(LAT)and nocturnal lowest blood oxygen saturation(LSaO2)],the Pittsburgh Sleep Quality Index(PSQI)score and the incidence of complications were compared between the two groups.Results In the observation group,the operation time,symptom relief time and hospital stay were significantly shorter than those in the control group,while the intraoperative bleeding volume was significantly less than that in the control group(P＜0.05).The VAS scores of the observation group at 6,24,48 and 72 h after operation were significantly lower than those of the control group(P＜0.05).At 3 days after operation,serum TNF-α,IL-4 and IL-8 levels in the observation group were significantly lower than those in the control group(P＜0.05);at 24 hours after operation,serum MDA level in the observation group was significantly lower than that in the control group,while the levels of SOD and GSH were significantly higher than those in the control group(P＜0.05);at 6 months after operation,AHI,ODI and LAT in the observation group were significantly lower than those in the control group,while the LSaO2 was significantly higher than that in the control group(P＜0.05);at 6 months after surgery,the PSQI score and incidence of complications in the observa-tion group were significantly lower than those in the control group(P＜0.05).Conclusion Tran-snasal endoscopic low temperature plasma radiofrequency ablation can reduce the levels of inflamma-tory factors,alleviate stress response,improve ventilation function,improve quality of sleep in chil-dren with snoring,and its safety is relatively high.
