Ultrasonic characteristics and diagnostic value of different molecular types of breast cancer with maximum diameter within 2 cm
- VernacularTitle:最大直径2 cm内的不同分子分型乳腺癌超声特征及诊断价值
- Author:
Xiaoyu CONG
1
;
Yingfen DA
;
Cheng WANG
;
Xinfeng LIANG
;
Min CHEN
;
Jie YUAN
Author Information
- Keywords: breast cancer; molecular classification; ultrasound examination; accuracy rate
- From: Journal of Clinical Medicine in Practice 2023;27(24):20-25
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the clinicopathological and ultrasonic characteristics of dif-ferent molecular types of breast cancer with maximum diameter ≤2 cm,and analyze the diagnostic val-ue of conventional ultrasound.Methods A total of 174 breast cancer patients with diameter ≤2 cm were selected as the study objects.According to the immunohistochemical results,they were divided in-to LA group(Luminal A,n=46),LB group(Luminal B,n=71),HER-2 group(HER-2 overexpres-sion type,n=11)and triple-negative group(triple-negative,n=46).The clinicopathology,ultrasonic characteristics and the accuracy of conventional ultrasonic diagnosis were analyzed.Results There were significant differences in breast cancer size,pathological grade and pathological type among four groups(P<0.05).Among the ultrasonic characteristics,there were statistically significant differ-ences in shape,edge,aspect ratio,calcification and rear echo among the four groups(P<0.05).Breast Imaging Reporting and Data System(BI-RADS)grading and accuracy of conventional ultra-sound diagnosis among the four groups showed statistically significant differences(P<0.05).Conclusion The clinicopathological features,ultrasound features and BI-RADS grading of different molecular types of breast cancer with maximum diameter ≤2 cm are different.Routine ultrasound has certain diagnostic value,which can provide important reference for molecular classification diagnosis,individualized treatment and prognosis evaluation of early breast cancer.