Research progress on molecular mechanism related to ventricular remodeling in elderly patients with chronic heart failure
- VernacularTitle:老年慢性心力衰竭心室重构相关分子机制的研究进展
- Author:
Rui YANG
1
;
Junmin YU
;
Xiaobo ZHANG
;
Dahe LI
;
Yuanyuan ZHAO
;
Hongye CHEN
Author Information
- Keywords: chronic heart failure; ventricular remodeling; senility; myocardial metabolism; exosomes
- From: Journal of Clinical Medicine in Practice 2023;27(23):139-143
- CountryChina
- Language:Chinese
- Abstract: Chronic heart failure is the terminal stage of progressive aggravation of various cardio-vascular diseases,and as an independent risk factor for heart failure,senility can increase the preva-lence rate.Ventricular remodeling is the main pathological and physiological basis of chronic heart failure,and in addition to changes in the activities of inflammatory reactions and related cytokines,factors such as metabolic disorders of myocardium,regulation of myocardial extracellular vesicles,and imbalance of intestinal microbiota also play important roles.This paper provided an overview of the research progress on ventricular remodeling mechanism in elderly patients with heart failure.
