Analysis on the results of 4 682 females with high-risk human papillomavirus infection in Yangzhou
10.7619/jcmp.201908025
- VernacularTitle:江苏扬州地区4682例女性高危型人乳头瘤病毒感染结果分析
- Author:
Songgang XIE
1
;
Ling ZHANG
Author Information
1. 江苏省苏北人民医院医学检测中心
- Keywords:
human papilloma virus;
high-risk type;
cervical cancer;
subtype distribution
- From:
Journal of Clinical Medicine in Practice
2019;23(8):88-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection rate, subtypes and distribution characteristics of human papilloma virus (HPV) women in Yangzhou. Methods A retrospective analysis was conducted on 4 682 female patients treated at Northern Jiangsu People's Hospital from May to September 2018. The fluorogenic quantitative PCR was used to detect high-risk HPV typing in cervical exfoliated cells and the results were statistically analyzed. Results A total of 936 positive samples were screened out in 4 682 subjects, the positive rate was 19. 99%, among whom 718 cases with single infection (76. 71%) and 218 with multiple infection (23. 29%) were included. The common subtypes of high-risk HPV infection were HPV 52, 16, 58 and 51, with the positive rate of 25. 00% (234/936), 20. 73% (194/936), 16. 67% (156/936) and 9. 94% (93/936), respectively. The infection rates of women in different age groups showed significant differences (P < 0. 05), and the higher positive rates distributed in age groups in descending sequence were as follows: 61 ~ 70 years old (32. 00%), 51 ~ 60 years old (26. 32%) and ≤20 years old (21. 43%). Conclusion The main HPV infection is single infection in Yangzhou. Common HPV subtypes are 52, 16, 58, 51, 39, and the patients among age groups have differed HPV subtypes.