Effect of medical polyethylene glycol berberine in improving the clinical outcomes after curettage
10.7619/jcmp.201908013
- VernacularTitle:医用聚乙二醇小檗碱液改善清宫术后临床结局的效果分析
- Author:
Wenjuan SHEN
1
;
Yuanyuan YE
;
Kaiyue ZHOU
;
Yixuan FU
;
Bai XUE
Author Information
1. 南京鼓楼医院集团宿迁市人民医院 妇产科
- Keywords:
curettage;
medical polyethylene glycol berberine;
intrauterine adhesions;
pregnancy
- From:
Journal of Clinical Medicine in Practice
2019;23(8):47-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of medical polyethylene glycol berberine on clinical outcomes after curettage. Methods A total of 166 curettage patients were divided into study group (n = 80) and control group (n = 86) by the patients' willingness. The two groups were given routine curettage, and the study group were additionally given 3 mL medical polyethylene glycol berberine by uterine cavity injection, while the control group infused no drugs. The postoperative endometrial thickness, menstruation situation were compared, and the re-pregnancy conditions of the patients in control group (n = 20) and experimental group (n = 32) with two-child requirement at follow-up and in one and a half year after follow-up were compared. Results The endometrial thickness in the study group was thicker than that in the control group [ (9. 44 ± 1. 95) mm vs. (8. 65 ± 2. 28) mm, P ＜ 0. 05], the proportion of the endometrial thickness ＜ 8 mm in the study group was lower than that in the control group[27. 5％ (22/80) vs. 38. 4％ (33/8), P ＜ 0. 01]. The ratio of patients with eumenorrhea was lower than that in the control group[ (10％ (8/80) vs. 16. 3％ (14/86) ], but there was no significant difference (P＞ 0. 05). The clinical pregnancy rate of the patients who had pregnancy requirements in the control group was higher than that in the control group [93. 75％ (30/32) vs. 70％ (14/20), P ＜ 0. 05]. Conclusion Medical polyethylene glycol berberine can promote the pregnancy rate. Meanwhile, the operation is simple and has higher compliance rate, which is an effective way in improving clinical outcomes.
