Intracranial Langerhans Cell Histiocytosis Presenting with Dysarthria and Gait Disturbance.
- Author:
Chang Gon YOU
1
;
Eun Jae LEE
;
Ho Sung RYU
;
Ji Hye HWANG
;
Bo Mi KIM
;
Sun Ju CHUNG
Author Information
1. Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sjchung@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Langerhans cell histiocytosis;
Neurodegenerative lesion
- MeSH:
Central Nervous System;
Dysarthria;
Gait;
Histiocytosis, Langerhans-Cell;
Humans;
Langerhans Cells;
Rare Diseases
- From:Journal of the Korean Neurological Association
2011;29(4):332-334
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Langerhans cell histiocytosis (LCH) is a rare disease of the monocyte-macrophage system involving clonal proliferation of Langerhans cells. Central nervous system (CNS) involvement of LCH occurs in 10-57% of all LCH cases. This disease is known to present in two ways in the CNS: intracranial tumorous lesions or intracranial nontumorous lesions (neurodegeneration). We report here an LCH patient who developed gait disturbance and dysarthria due to neurodegenerative lesions associated with LCH.
