Retrospective study on diagnosis and treatment of patients with early-stage renal artery stenosis after allograft kidney transplantation
10.7619/jcmp.201809003
- VernacularTitle:同种异体肾移植术后早期肾动脉狭窄诊疗的回顾性研究
- Author:
Yanhong YANG
1
;
Enyuan LI
;
Hao CHEN
;
Li SUN
;
Jun TAO
;
Zhijian HAN
;
Ruoyun TAN
;
Xiaobing JU
;
Min GU
Author Information
1. 南京医科大学附属第一医院泌尿科
- Keywords:
transplant renal artery stenosis;
serum creatinine;
color Doppler ultrasound;
percutaneous transluminal angioplasty
- From:
Journal of Clinical Medicine in Practice
2018;22(9):11-15
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the early diagnosis and treatment for transplant renal artery stenosis (TRAS) through single-center retrospective study.Methods Clinical manifestation,laboratory tests and imaging data in 287 patients underwent renal transplantation in our center were analyzed retrospectively.Ultrasound parameters in TRAS patients and non-TRAS patients was compared to discover the thresholds of some CDUS parameters.Changes of ultrasound parameter and serum creatinine in TRAS patients and non-TRAS patients were compared.The changes of blood pressure and serum creatinine before and after percutaneous transluminal angioplasty (PTA) were observed.Results Totally 13 cases had TRAS in the 287 patients.Renal artery PSV ＞ 250 cm/s,interlobar artery resistance index (RI) ＜0.51,PSV ratio of the renal artery to the interlobar artery ＞ 10 were considered as the color doppler ultrasound (CDUS) diagnostic threshold.Symptomatic TRAS patients and asymptomatic TRAS patients were treated by PTA,and the serum creatinine and mean arterial pressure significantly decreased (P ＜ 0.05).Conclusion Monitoring renal allograft blood flow and clinical manifestation after renal transplantation is helpful for early diagnosis of TRAS in the postoperatively follow-up.Transplant renal artery PSV ＞ 250 cm/s,interlobar artery RI ＜ 0.51 and PSV ratio of the renal artery to the interlobar artery ＞ 10 can be considered as the CDUS diagnostic threshold.
