Clinical effect observation of argon-helium knife combined with pemetrexed on the treatment of patients with advanced non-small cell lung cancer
10.7619/jcmp.201803020
- VernacularTitle:氩氦刀联合培美曲塞化疗治疗老年晚期非小细胞肺癌的临床疗效观察
- Author:
Peng GU
1
;
Mo LIU
;
Xiwen FAN
Author Information
1. 新疆医科大学附属肿瘤医院
- Keywords:
argon helium knife;
pemetrexed;
non-small cell lung cancer;
clinical efficacy
- From:
Journal of Clinical Medicine in Practice
2018;22(3):72-74,78
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy of argon-helium knife combined with pemetrexed in the treatment of patients with advanced non-small cell lung cancer.Methods Totally 80 patients with advanced non-small cell lung cancer (NSCLC) were selected and randomly divided into control group and study group,40 cases in each group.The patients in the control group were treated with argon-helium knife,and the patients in the study group were treated with pemetrexed and argon-helium knife treatment.The adverse reactions,quality of life and clinical efficacy were compared between two groups.Results After treatment,the incidence rate of adverse reactions in the study group was 5％,which was similar with 7.5％ in the control group (P ＞ 0.05).After treatment,the MOS SF-36 increased significantly in both groups,and the study group was significantly higher than the control group (P ＜ 0.05).In the study group,the total effective rate was 92.5％,which was significantly higher than 47.5 ％ in the control group (P ＜ 0.05).Conclusion Argon-helium knife combined with pemetrexed shows a high effective rate in treating patients with advanced non-small cell lung cancer.
