Clinical value of combined detection of Hcy, Cys C,D-D and hs-CRP in predicting prognosis of patients with pregnancy induced hypertension
10.7619/jcmp.201803010
- VernacularTitle:同型半胱氨酸、胱抑素C、D-二聚体、超敏C反应蛋白联合检测预测妊娠高血压患者预后的价值分析
- Author:
Dandan WANG
1
;
Hongyu LI
;
Shiwen JU
Author Information
1. 蚌埠医学院第二附属医院妇产科
- Keywords:
Hcy;
Cys C;
D-D;
hs-CRP;
pregnancy induced hypertension;
combined detection
- From:
Journal of Clinical Medicine in Practice
2018;22(3):38-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of combined detection of Hcy,Cys C,D-D and hs-CRP in predicting prognosis of patients with pregnancy induced hypertension.Methods A total of 105 patients with pregnancy induced hypertension treated in our hospital were selected as pregnancy induced hypertension group,and 60 single pregnant women with the same gestational age were selected as control group.The serum levels of Hcy,Cys C,D-D and hs-CRP were measured in all patients.The preeclampsia pregnancy induced hypertension patients were divided into mild preeclampsia subgroup (n =45) and severe preeclampsia subgroup (n =60) according to the blood pressure.The indicators of each group and its correlation with the degree of pre eclampsia were observed.Results The levels of Hcy,Cys C,D-D and hs-CRP in the pregnancy induced hypertension group were significantly higher than that in the control group (P ＜ 0.05).Severe preeclampsia subgroup had higher Hcy,Cys C,D-D and hs-CRP levels than mild preeclampsia subgroup (P ＜ 0.05).The joint detection of the above indicators had higher sensitivity and specificity than single detection (P ＜0.05).Conclusion The indicators of Hcy,Cys C,D-D and hs-CRP are significantly and positively correlated with the stage of preeclampsia in pregnancy induced hypertension.The sensitivity and specificity of the combined detection of Hcy,Cys C,D-D and Hs-CRP levels are significantly better than that of single detection,so it has better clinical value.
