Analysis of distribution and drug resistance of pathogens related to bloodstream infection in intensive care unit
- VernacularTitle:重症监护病房相关血流感染的病菌分布以及耐药特性分析
- Author:
Bei LIANG
1
;
Yang YANG
;
Xiaopeng LI
;
Huan YE
Author Information
- Keywords: intensive care unit; bloodstream infection; pathogen distribution; drug resistance characteristics
- From: Journal of Clinical Medicine in Practice 2018;22(1):7-9,13
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the distribution and drug resistance of pathogens in bloodstream infection in intensive care unit.Methods A total of 98 patients with bloodstream infection caused by indwelling catheter in our hospital in intensive care unit were selected.The blood samples applied drug susceptibility test and bacterial identification to analyze the distribution and drug resistance of the bacteria.Results A total of 108 strains of pathogens in 98 patients were isolated,among which 45 strains were Gram-positive bacteria,58 were Gram-negative bacteria,5 were fungi.Grampositive bacteria were mainly Staphylococcus epidermidis,Staphylococcus aureus,and Saphylococcus haemolyticus,and Gram-negative bacteria were mainly Escherichia coli,Pseudomonas aeruginosa and Klebsiella pneumoniae.Major Gram-negative bacteria have a higher sensitivity to imipenem,cefoperazone/sulbactam,piperacillin/tazobactam,amikacin,and lower resistance rates,while Bowman acinetobacter resistance to bacteria were at a high level,while Klebsiella pneumoniae had lower resistance rate.The main gram-positive bacteria had higher sensitivity on vancomycin,linezolid,tigecycline,and penicillin G resistance was generally higher.Conclusion Gram-negative bacteria are the main pathogens of patients with bloodstream infection caused by indwelling catheter and drugs usage according to drug sensitivity test results can reduce drug resistance.
