Application of dexmedetomidine combined with preemptive analgesia with dezocine in the treatment of patients with PPH surgery
10.7619/jcmp.201721018
- VernacularTitle:右美托咪定复合地佐辛超前镇痛在肛肠科吻合器痔上黏膜环切术中的应用
- Author:
Yupei CUI
1
;
Su LIU
;
Shanshan MAO
;
Yong CAO
;
Jing LIU
Author Information
1. 徐州医科大学麻醉学院
- Keywords:
dexmedetomidine;
dezocine;
preemptive analgesia;
procedure for prolapse and hemorrhoids
- From:
Journal of Clinical Medicine in Practice
2017;21(21):62-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of dexmedetomidine combined with the preemptive analgesia with dezocine on the treatment of patients with prolapse and prolapse of hemorrhoids (PPH).Methods A total of 60 patients with PPH were randomly divided into dexmedetomidine + dezocine group (group A) and normal saline + dezocine group (group B).All patients received lowdose saddle anesthesia,and at the time points of saddle anesthesia fixed plane (T0),firing the stapler (T1) and at the end of operation (T2),systolic blood pressure (SBP),diastolic blood pressure (DBP),heart rate (HR),Ramsay sedation score,the incidence of postoperative analgesic effect and complications were compared between two groups.Results At T1 and T2,the SBP,DBP and HR of group A were significantly lower than those of group B (P ＜ 0.05),and the score of Ramsay sedation was significantly higher than that of group B (P ＜ 0.05).The analgesic effect VAS scores of group A at 4,8,12,24 and 48 h after operation were significantly lower than those in group B (P ＜0.05).There was no significant difference in anal distention and discomfort between the two groups (P ＞ 0.05).There were significant differences in the incidence of urinary retention,nausea and vomiting,and nocturnal sleep disorders between the two groups (P ＜ 0.01).Conclusion Dexmedetomidine combined with preemptive analgesia with dezocine is effective in treatment of patients with PPH surgery.
