Change of immunologic function in children with mycoplasma pneumoniae pneumonia
- VernacularTitle:肺炎支原体肺炎患儿免疫功能的变化
- Author:
Liwen XUE
1
;
Chenlu FU
;
Yibo ZHUANG
Author Information
- Keywords: mycoplasma pneumoniae pneumonia; T lymphocyte subsets; humoral immunity
- From: Journal of Clinical Medicine in Practice 2017;21(21):39-41
- CountryChina
- Language:Chinese
- Abstract: Objective To observe the change of immunologic function in children with mycoplasma pneumoniae pneumonia (MMP).Methods Totally 114 children diagnosed with MPP were selected as experimental group,and MPIgM were positively detected in the course of 7 to 10 days,and the blood samples were collected.At the same time,50 healthy children in health clinic were selected as control group,and peripheral blood samples were collected.The levels of T cell subsets (CD3,CD4,CD8,CD4/CD8,NK) and humoral immunity (IgG,IgA,IgM,C3,C4) in peripheral blood samples were detected respectively.Results The serum CD3,CD4,CD4/CD8 ratio and NK value in the experimental group were significantly lower than those in the control group (P ＜ 0.05),and IgA,C3 and C4 were significantly lower than those in the control group (P ＜ 0.05),but there was no significant difference in IgG and IgM values (P ＞ 0.05).Conclusion Mycoplasma pneu moniae (MP) infection can cause immune dysfunction,inhibit cellular immunity and humoral immunity.
