Detection of multiple viral antigens in pediatric patients with respiratory infection in Yangzhou
10.7619/jcmp.201719025
- VernacularTitle:江苏省扬州地区儿童呼吸道感染病毒病原学调查分析
- Author:
Wenguo CHENG
1
;
Jian CHEN
;
Yan LIU
;
Xinlin ZHU
;
Jun ZHU
Author Information
1. 扬州大学附属医院扬州市妇幼保健院检验科
- Keywords:
respiratory tract infections;
children;
viruses;
direct immunofluorescence assay
- From:
Journal of Clinical Medicine in Practice
2017;21(19):87-90
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate multiple viral antigens in pediatric patients with respiratory infection in Yangzhou.Methods A total of 17 691 children with respiratory infection admitted in our hospital between January 2011 and December 2011 were tested with direct immunof-luorescence method.A total of 7 kinds of virus antigens were detected,including adenovirus (ADV),respiratory syncytial virus (RSV),parainfluenza virus Ⅰ,Ⅱ,Ⅲ(PIV Ⅰ,Ⅱ,Ⅲ),influenza virus A/B(IFA/B).Its epidemiological characteristics was analyzed.Results There were altogether 1 991 positive cases,the detection rate was 11.25％ (1 991/17 691),in which the proportion of RSV was 60.12％ (1 197/1991),followed by PIV llⅢ 14.27％ (284/1 991),ADV 8.04％ (160/1 991),PIV Ⅰ 5.42％ (108/1 991),IFA5.27％ (105/1 991),IFB 4.07％ (81/1 991),PIVⅡ 2.81％ (56/1 991).There was significant difference between male and female in the detection rate of respiratory virus.Respiratory virus detected rate in 1 month to ＜ 1 year old was 59.81％ (1 191/1 991),single virus detection rate was the highest.The detection rate of virus for positive was the highest in winter,accounting for 51.88％ (1 033/1 991),and the lowest in summer for 10.35％ (206/1 991).Conclusion Respiratory virus infection in Yangzhou is influenced by age,season and gender,with infants and young children aged 1 month to 1 year in high-risk infection,and RSV infection occurs mostly,and the male are most likely to be infected in winter.
