Application of somatostatin combined with parenteral nutrition in the conservative treatment of patients with colorectal cancer complicated with intestinal obstruction
10.7619/jcmp.201713017
- VernacularTitle:生长抑素联合肠外营养支持在大肠癌合并肠梗阻患者保守治疗中的应用研究
- Author:
Yongze DAI
1
;
Dahai WANG
;
Xiaoming LU
Author Information
1. 湖北省黄梅县人民医院 普外科
- Keywords:
somatostatin;
parenteral nutrition;
colorectal cancer;
intestinal obstruction
- From:
Journal of Clinical Medicine in Practice
2017;21(13):64-66,71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application of somatostatin combined with parenteral nutrition in the treatment of patients with colorectal cancer complicated with intestinal obstruction.Methods A total of 66 patients with colorectal cancer complicated with intestinal obstruction were randomly divided into experimental group and control group,33 cases in each group.The control group was treated with parenteral nutrition,gastrointestinal decompression,conventional treatment for water electrolyte imbalance,while experimental group was treated with intravenous infusion of somatostatin on the basis of the control group.Clinical indicators,blood indexes,metabolic disorders,clinical curative effect were compared between two groups.Results In the experimental group,abdominal pain remission rate and anal exhaust defecation remission rate were significantly higher than the control group,abdominal pain,anal exhaust defecation or disappearance time recovery time were significantly less than the control group,and gastrointestinal decompression drainage was significantly lower than the control group(P<0.05).After treatment,the blood indexes such as albumin,pre albumin,CRP,TNF-α,hemoglobin,WBC in experimental group were significantly better than those in the control group(P<0.05).In the experimental group,blood glucose abnormalities,abnormal blood glucose and abnormal rate of blood sodium were significantly lower than the control group
