Predictive effect of serum PCT and T cell subsets on treatment of patients with intra-cerebral hemorrhage
10.7619/jcmp.201711008
- VernacularTitle:血清降钙素原和T细胞亚群对脑出血患者感染的预测效果
- Author:
Dan CHEN
1
;
Li YU
;
Ding LONG
Author Information
1. 湖北省武汉市中心医院
- Keywords:
PCT;
T cell subsets;
cerebral hemorrhage;
infection;
prediction
- From:
Journal of Clinical Medicine in Practice
2017;21(11):25-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive effect of serum PCT and T cell subsets on treatment of patients with cerebral hemorrhage infection.Methods A total of 80 patients with cerebral hemorrhage were divided into infection group and non-infection group.Serum PCT and T cell subsets were compared.Clinical data of patients were analyzed by multivariate Logistic regression analysis,and ROC curve was used to evaluate the effect of PCT and T cell subsets on cerebral hemorrhage infection.Results Serum PCT and CD8+ in the infection group were significantly higher than non-infected group,while CD3+,CD4+,CD4+/CD8+ were significantly lower than the non-infection group (P<0.05).The NIHSS score on admission,serum PCT,CD3+,CD4+/CD8+ were independent risk factors for infection in patients with intra-cerebral hemorrhage (P<0.05).The ROC curves of serum PCT,CD4+/CD8+ were 0.833,0.869,which showed good predictive effect for cerebral hemorrhage infection (P<0.05).Conclusion Serum PCT and T cell subsets are independent risk factors for infection in patients with intra-cerebral hemorrhage.
