Influencing factors of perioperative myocardial injury in coronary heart disease patients with PCI
10.7619/jcmp.201711002
- VernacularTitle:冠心病患者PCI围术期心肌损伤的影响因素
- Author:
Jinping REN
1
Author Information
1. 北京怀柔医院
- Keywords:
percutaneous coronary intervention;
rosuvastatin;
apolipoprotein A;
perioperative myocardial damage;
coronary heart disease
- From:
Journal of Clinical Medicine in Practice
2017;21(11):5-7,11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of perioperative myocardial injury in coronary heart disease patients with PCI.Methods Clinical materials of 87 coronary heart disease patients with PCI were retrospectively analyzed,including 23 stable angina pectoris patients (SAP) and 64 unstable angina pectoris patients (SAP).The general information,PCI operation related data,the perioperative myocardial injury and myocardial infarction were compared between two groups.The influencing factors of perioperative myocardial injury in coronary heart disease patients with PCI were analyzed by Logistic regression.The level of blood fat was compared between patients with administration of rosuvastatin >1 month and ≤ 1 month.Results There was no significant difference of general information between two groups (P>0.05).In the SAP group,the number of SAP patients with stent implantation was significantly higher than that of UAP group (P<0.05).There was no significant difference between the two groups in myocardial injury,myocardial infarction,and the level of hs-CRP after PCI (P>0.05).The incidence of myocardial damage in patients with PCI during perioperative period was associated with apolipoprotein A,preoperative statin use,preoperative statin dose therapy,and total length of the stent (P<0.05).At the time of on admission and preoperative,TC and LDL levels of patients with use of statins over one month before operation on admission was significantly lower than patients with use of statins less than one month (P<0.05).Conclusion The loading of apolipoprotein A expression,use of rosuvastatin before PCI,use of statin over 1 month are closely related with the decrease of myocardial injury rate in perioperative period of PCI,and the total length of intra-coronary stent implantation is associated with increasing incidence of myocardial damage.
