Effects of oxiracetam combined with rosuvastat on levels of serum hs-CRP, IL-1β and IL-6 in patients with cerebral infarction
10.7619/jcmp.201705009
- VernacularTitle:奥拉西坦联合瑞舒伐他汀对脑梗死患者血清超敏C反应蛋白、白细胞介素-1β、白细胞介素-6的影响
- Author:
Hui XIA
1
;
Tingting HU
;
Wen LIU
;
Chang ZHOU
;
Timing LU
Author Information
1. 东南大学附属中大医院江北院区神经内科
- Keywords:
oxiracetam;
rosuvastatin;
cerebral infarction;
hs-CRP;
IL-1 β;
IL-6
- From:
Journal of Clinical Medicine in Practice
2017;21(5):32-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of oxiracetam combined with rosuvastatin on levels of serum hs-CRP,IL-1 β and IL-6 in patients with cerebral infarction.Methods A total of 100 patients with cerebral infarction were selected and randomly divided into observation group and control group.The control group was given conventional cerebral infarction treatment,and the observation group was given oxiracetam combined with rosuvastatin.The clinical efficacy and levels of hsCRP,IL-1β and IL-6 before and 14 days after treatment were compared.Results After treatment,the total effective rate of the observation group was significantly higher than the control group (P ＜0.05).After treatment,the levels of hs-CRP,IL-1β,IL-6 improved significantly in both groups (P ＜ 0.05),and which in the observation group was significantly better than control group (P ＜0.05).Conclusion Oxiracetam combined with rosuvastatin is effective in treatment of patients with cerebral infarction,and it can significantly improve the levels of hs-CRP,IL-1 β and IL-6.
