Correlation between breast ultrasound data classification system and estrogen receptor, progesterone receptor, proto-oncogene
10.7619/jcmp.201701031
- VernacularTitle:乳腺癌超声数据分级系统与雌激素受体、孕激素受体、原癌基因的相关性
- Author:
Meiying LI
1
;
Yang WU
;
Yanjuan XIA
;
Lijie ZHANG
;
Xingang GU
Author Information
1. 上海市中医药大学附属普陀区中心医院超声科
- Keywords:
breast cancer;
ultrasound;
pathology
- From:
Journal of Clinical Medicine in Practice
2017;21(1):103-105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between breast ultrasound data classification system (BI-RADS) and estrogen receptor (ER),progesterone receptor (PR),proto-oncogene (Cerb-2).Methods The IDC ultrasound imaging of 320 patients diagnosed as breast cancer by surgery and postoperative pathology wasanalyzed,including the size of the lump,edge burr,aspect ratio,the presence of microcalcification,mass internal blood flow of posterior acoustic attenuation,mass,elasticity ratings and mass BI-RADS classification,and the expressions of ER,PR and CerB-2 were detected by immunohistochemical method.Results The positive rates of PR and ER in the mass with burr edge were significantly higher than those in the mass without burr edge,the positive rate of Cerb2 in mass with slight calcifications was significantly higher than that in mass without slight calcifications,and the positive rate of Cerb-2 in mass with flow grade Ⅱ ～Ⅲ was significantly higher than that in mass with flow grade 0 ～ I.The expressions of BI-RADS in mass with positive ER,PR and CerbB2 were significantly higher than those in mass with negative ER,PR and CerbB-2 (P ＜ 0.05).Conclusion There are correlations between molecular biology of breast cancer and edge burr,microcalcification and rich blood flow.
